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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: E2F8 All Species: 26.67
Human Site: S117 Identified Species: 73.33
UniProt: A0AVK6 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A0AVK6 NP_078956.2 867 94166 S117 Q P S R K E K S L G L L C H K
Chimpanzee Pan troglodytes XP_508325 867 94169 S117 Q P S R K E K S L G L L C H K
Rhesus Macaque Macaca mulatta XP_001095088 867 94195 S117 Q P S R K E K S L G L L C H K
Dog Lupus familis XP_534087 864 93661 S117 Q P S R K E K S L G L L C H K
Cat Felis silvestris
Mouse Mus musculus Q58FA4 860 93258 S117 Q P S R K E K S L G L L C H K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506156 878 95490 S116 Q P S R K E K S L G L L C H K
Chicken Gallus gallus
Frog Xenopus laevis NP_001084876 724 79575
Zebra Danio Brachydanio rerio XP_694311 917 100437 S130 H I S R K D K S L G L L C Y K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002321561 384 43173
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.6 89.6 N.A. 83 N.A. N.A. 73.8 N.A. 48 39.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 98.1 94.2 N.A. 88.5 N.A. N.A. 82.1 N.A. 59.9 55.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 100 N.A. 0 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 100 N.A. 0 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 20.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 30.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 0 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 78 0 0 % C
% Asp: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 67 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 78 0 0 0 0 0 % G
% His: 12 0 0 0 0 0 0 0 0 0 0 0 0 67 0 % H
% Ile: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 78 0 78 0 0 0 0 0 0 0 78 % K
% Leu: 0 0 0 0 0 0 0 0 78 0 78 78 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 78 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 78 0 0 0 0 78 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _